New Nanotechnique Monitors ER Stress Biomarker for ADTKD

New Nanotechnique Monitors ER Stress Biomarker for ADTKD
Yeawon Kim, a member of the Y. Maggie Chen Lab, is first author of the study titled “Ultrabright Plasmonic-Fluor Nanolabel-Enabled Detection of a Urinary ER Stress Biomarker in Autosomal Dominant Tubulointerstitial Kidney Disease (ADTKD),”published, in the American Journal of Physiology – Renal Physiology as an Innovative Methodology article. (Authors: Yeawon Kim, Zheyu Wang, Chuang Li, Kendrah Kidd, Yixuan Wang, Bryce […]

Chuang’s Review Paper Is In Press

Chuang’s Review Paper Is In Press
Chuang has published his review “Endoplasmic Reticulum-Associated Biomarkers for Molecular Phenotyping of Rare Kidney Disease” in International Journal of Molecular Sciences today

Sun-Ji Published Her Review Article in AJP

Sun-Ji Published Her Review Article in AJP
Sun-Ji’s review article “Endoplasmic Reticulum Calcium Homeostasis in Kidney Disease: Pathogenesis and Therapeutic Targets” has been published in American Journal of Pathology this month.

Maggie to Serve on ASN Grants Review Committee

Maggie to Serve on ASN Grants Review Committee
American Society of Nephrology and KidneyCure (ASN Foundation) have invited Maggie, MD, PhD, associate professor of medicine in the Division of Nephrology, Washington University, to serve on their ASN Grants Review Committee. Established in 2012, KidneyCure currently provides over $3 million per year to nephrology fellows and new investigators to help facilitate in their transition […]

Maggie Is Appointed to FACA Nephrology Subcommittee

Maggie Is Appointed to FACA Nephrology Subcommittee
Maggie has been appointed as a special government employee to the Federal Advisory Committee Act (FACA) Nephrology Subcommittee. Subcommittee members provide scientific peer review of Department of Veterans Affairs (VA) research program applications submitted to Biomedical Laboratory Research and Development and Clinical Science Research and Development Services.  Chen will serve on the nephrology panel to […]

We are awarded an NU GoKidney Grant

We are awarded an NU GoKidney Grant
We are awarded a Northwestern University George M. O’Brien Kidney Core Center (NU GoKidney) Pilot and Feasibility Grant.  NU GoKidney is a kidney research center that fosters research leading to the discovery of novel nephrotherapeutics that will transform the prevention and treatment of kidney diseases and eventually lead to cures. The center’s goal is to […]

We have received a $1.8M DoD grant

We have received a $1.8M DoD grant
Maggie is awarded a $1.8 million grant from the U.S. Department of Defense for her study “Develop Novel Podocyte Endoplasmic Reticulum (ER) Calcium Stabilizers to Treat Focal Segmental Glomerulosclerosis (FSGS).” FSGS is the most common primary glomerulopathy leading to renal failure and disproportionately affects African-Americans, a highly represented population among military personnel and Veterans. While […]

We are awarded a $300K WUSM-Mallinckrodt Challenge grant

We are awarded a $300K WUSM-Mallinckrodt Challenge grant
Maggie is the recipient of a 2-year, $300,000 Mallinckrodt Challenge Grant for her study “Targeting Podocyte Dysfunctional Ryanodine Receptor to Treat Nephrotic Syndrome.” The overall goals of this proposal are to determine the molecular mechanisms underlying increased podocyte endoplasmic reticulum (ER) calcium efflux under ER stress. The proposed study could lead to a significant leap […]

Sun-Ji’s paper is published in PNAS

Sun-Ji’s paper is published in PNAS
A new study first-authored by Sun-Ji Park, found a new class of drugs that shows great promise in the treatment of nephrotic syndrome (NS) resulting from podocyte endoplasmic reticulum (ER) dysfunction. NS is a leading cause of chronic kidney disease affecting over 500 million people worldwide. Damage to podocytes, the highly specialized epithelial cells that […]

Maggie Receives Center for Drug Discovery Investigator Matching Grant

Maggie Receives Center for Drug Discovery Investigator Matching Grant
Maggie just received an Investigator Matching Micro Grant funded by the Center for Drug Discovery (CDD) at Washington University for her proposal titled Development of a Novel Biotherapeutic Protein to Treat Endoplasmic Reticulum Stress-Mediated Kidney Disease. Although accumulating evidence has highlighted the important role of endoplasmic reticulum (ER) stress in the pathogenesis of various glomerular […]